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Other Chaperones
 

Molecular chaperones are important in cellular protein production. Some chaperones are involved in protein folding. Others are required for protein secretion. Still others are needed for disulfide bond formation. Absent or insufficient chaperones result in non-insoluble, unstable, or dysfunctional recombinant proteins. Chaperones are critical for the function of many proteins.

We engineered cell strains over express one or more molecular chaperones. Some of these chaperones are important for protein folding such as GroE and dnaKJ. Others are involved in peptidyl-prolyl-cis-trans-isomerization like trigger factor, PI and PPI. Dsb A, B, and C are critical for disulfide bond formation. skp promotes protein secretion.

Other factors also affect protein solubility, stability, and activity. Please click on respective word for more information.

Other chaperone strains:

Strain Name

Cat#

Gene

Description

Price (US$)
PlusEaTM 10310 GroE GroE contains GroES+EL E.coli chaperones 350
PlusKJaTM 10320 dnaKJ dna KJ contains dnaK+J E.coli chaperones 350
PlusDAaTM 10330 Dsb A Dsb A promotes disulfide bond formation 350
PlusDBaTM 10340 Dsb B Dsb B promotes disulfide bond formation 350
PlusDCaTM 10350 Dsb C Dsb C promotes disulfide fond formation 350
PlusTaTM 10360 Trx Thioredoxin increases solubility of proteins 350
PlusSaTM 10370 skp skp promotes protein secretion 350
PlusTFaTM 10380 trigger factor involves in protein folding, solubility and stability 350
PlusPIaTM 10390 PI peptidyl-prolyl-cis-trans-isomerase (PI) 350
PlusPPIaTM 10400 PPI periplasmic peptidyl-prolyl-cis-trans-isomerase (PPI) 350
PlusXLaTM 10410 RXR LBD Human retinoid X receptor β ligand binding domain 350
PlusEbTM 10311 GroE GroE contains GroES+EL E.coli chaperones 350
PlusKJbTM 10321 dnaKJ dna KJ contains dnaK+J E.coli chaperones 350
PlusDAbTM 10331 Dsb A Dsb A promotes disulfide bond formation 350
PlusDBbTM 10341 Dsb B Dsb B promotes disulfide bond formation 350
PlusDCbTM 10351 Dsb C Dsb C promotes disulfide fond formation 350
PlusTbTM 10361 Trx Thioredoxin increases solubility of proteins 350
PlusSbTM 10371 skp skp promotes protein secretion 350
PlusTFbTM 10381 trigger factor involves in protein folding, solubility and stability 350
PlusPIbTM 10391 PI peptidyl-prolyl-cis-trans-isomerase (PI) 350
PlusPPIbTM 10401 PPI periplasmic peptidyl-prolyl-cis-trans-isomerase (PPI) 350
PlusXLbTM 10411 RXR LBD Human retinoid X receptor β ligand binding domain 350

All the strain names ending  with "a" are used in the expression with E.coli RNA polymerase and strain names ending with "b" are used in the expression with T7 RNA polymerase. The expression level of the specified gene in the two strains are comparable. All of the cell strains with TM superscripts are trademarks of Expression Technologies Inc. They are all patent-pending. These cell strains are for non-commercial research use only and they cannot be distributed out of the purchasing lab. Please contact us for any other uses.

Warranty

These cell strains are guaranteed to express the specified genes. In the case that the cell has an endogenous gene, the specified gene is overexpressed at least three times more than the endogenous expression level. Please email us at info@exptec.com for more information.


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